Milena Smit was born on 5 October 1996 in Elche, Spain. She first started working in show business as a model when she was 15 years old. She worked in her home city and later moved to Madrid in search of career opportunities. Her father is Dutch.
She trained as an actress at the Cristina Rota acting school and was taught by Bernard Hiller, an acting coach of such actors as Leonardo DiCaprio and Cameron Diaz. Before becoming an actress, she was a waitress, shop assistant, babysitter, and information assistant on the subway.
Smit's first film appearances were in various short films such as Diagonales, Innermost, Chimichanga, and Adentro. In 2020, she appeared in her first feature film, Cross the Line, directed by David Victori with Mario Casas. For her work on the film, she was nominated at the Goya Awards for best new actress. The film's casting team discovered the actress via a social network: "After much searching, we found Milena on Instagram. We fell in love with everything she h